G6019
Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes
lyophilized powder, 50-150 units/mg protein
Synonym(s):
D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
form
lyophilized powder
Quality Level
specific activity
50-150 units/mg protein
composition
Protein, 40-70% biuret
UniProt accession no.
foreign activity
3-Phosphoglyceric phosphokinase ≤2%
storage temp.
−20°C
Gene Information
human ... GAPDH(2597)
Related Categories
Biochem/physiol Actions
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.
Physical form
Lyophilized powder containing sodium citrate buffer salts
Other Notes
One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
高风险级别生物产品--人源产品
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Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 8), 978-980 (2012-08-08)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces
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Articles
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
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