Skip to Content
Merck
CN

Key Documents

View All Documentation

G6752

Guanosine

≥98%

Synonym(s):

9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C10H13N5O5
CAS Number:
118-00-3
Molecular Weight:
283.24
PubChem Substance ID:
24895268
UNSPSC Code:
41106305
MDL number:
MFCD00010182
NACRES:
NA.51
EC Number:
204-227-8
Beilstein/REAXYS Number:
625911
Assay:
≥98%
Biological source:
microbial
Form:
powder
Solubility:
formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

microbial

Quality Level

200

assay

≥98%

form

powder

mp

250 °C (dec.) (lit.)

solubility

formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

SMILES string

[H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

InChI key

NYHBQMYGNKIUIF-UUOKFMHZSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.

Application

Guanosine has been used:
  • as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
  • as a component of Mouse Embryonic Fibroblasts (MEFs) culture
  • as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

Biochem/physiol Actions

Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM4753
BCCM2782
BCCL5219
BCCL7461
BCCJ8525

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury
Kelly KJ, et al.
The Journal of Clinical Investigation, 108(9), 1291-1298 (2001)
Guanosine: a neuromodulator with therapeutic potential in brain disorders
Lanznaster D, et al.
Aging and disease, 7(5), 657-657 (2016)
Qualitative and quantitative analysis of glucosinolates and nucleosides in Radix Isatidis by HPLC and liquid chromatography tandem mass spectrometry
Wang X, et al.
Acta Pharmaceutica Sinica. B, 3(5), 337-344 (2013)
mTORC1 couples nucleotide synthesis to nucleotide demand resulting in a targetable metabolic vulnerability
Valvezan AJ, et al.
Cancer Cell, 32(5), 624-638 (2017)
Variations in genomic DNA methylation during the long-term in vitro proliferation of oil palm embryogenic suspension cultures
Rival A, et al.
Plant Cell Reports, 32(3), 359-368 (2013)
View All Related Papers

Global Trade Item Number

SKUGTIN
G6752-100G04061833640791
G6752-500G04061833620564
G6752-1G04061833640876
G6752-25G04061833640975

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service