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G7127

Guanosine 5′-diphosphate sodium salt

Name: Guanosine 5′-diphosphate sodium salt
Brand: SIGMA

Type I, ≥96% (HPLC)

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Synonym(s):

GDP

Empirical Formula (Hill Notation):

C₁₀H₁₅N₅O₁₁P₂

CAS Number:

43139-22-6

Molecular Weight:

443.20

MDL number:

MFCD00070121

PubChem Substance ID:

24895291

NACRES:

NA.51

biological source

synthetic (organic)

Quality Level

300

type

Type I

Assay

≥96% (HPLC)

form

powder

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)c2N1

InChI

1S/C10H15N5O11P2.Na.H/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;

InChI key

PVMPTWQLNDHIEV-UHFFFAOYSA-N

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Nucleosides and Nucleotides

Application

Guanosine 5′-diphosphate sodium salt has been used:

in GTP-γ-35S functional assays
in Y1 agonist-stimulated [35S]- guanosine-5′-O-(3-thio)triphosphate (GTPγS) functional binding
in the expression and purification of recombinant proteins

Biochem/physiol Actions

Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Protocols

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