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G7637

Guanosine 5′-[β-thio]diphosphate trilithium salt

Name: Guanosine 5&#8242;-[&#946;-thio]diphosphate trilithium salt
Brand: SIGMA

≥85% (HPLC), G-protein inhibitor, powder

Synonym(s):

GDPβS trilithium salt, GDP-β-S, GDP-β-S-Li₃

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₂Li₃N₅O₁₀P₂S

CAS Number:

97952-36-8

Molecular Weight:

477.07

NACRES:

NA.77

PubChem Substance ID:

329799966

UNSPSC Code:

41106305

MDL number:

MFCD00057735

Beilstein/REAXYS Number:

8181243

Assay:

≥85% (HPLC)

Form:

powder

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Properties

Product Name

Guanosine 5′-[β-thio]diphosphate trilithium salt, ≥85% (HPLC), powder

Quality Segment

200

assay

≥85% (HPLC)

form

powder

color

white

solubility

H₂O: 20 mg/mL (Solutions are very unstable; prepare immediately prior to use.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H15N5O10P2S.3Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1

InChI key

LMCWQGPJYZRMKU-CYCLDIHTSA-K

Description

Application

Guanosine 5′-[β-thio]diphosphate trilithium salt has been used as an inhibitor of G-protein activation to study its effects on acetylcholine current in bag cell neurons. It has also been used to study its effects on cholinergic-dependent plateau potentials.

Biochem/physiol Actions

Guanosine 5′-[β-thio]diphosphate is a non-hydrolyzable analog of guanosine. It functions as an inhibitor of G-protein activation.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

Non-hydrolyzable GDP analog

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c