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G8377

Guanosine 5′-monophosphate disodium salt hydrate

≥99%,from yeast, powder

Synonym(s):

5′-GMP-Na2, 5′-Guanylic acid disodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C10H12N5Na2O8P · xH2O
CAS Number:
5550-12-9
Molecular Weight:
407.18 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
24895338
UNSPSC Code:
41106305
EC Number:
226-914-1
MDL number:
MFCD00151238
Beilstein/REAXYS Number:
3586801
Assay:
≥99%
Biological source:
yeast
Form:
powder
Solubility:
H2O: soluble 50 mg/mL, clear, colorless to faintly yellow
Storage temp.:
room temp
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Product Name

Guanosine 5′-monophosphate disodium salt hydrate, from yeast, ≥99%

biological source

yeast

Quality Segment

200

assay

≥99%

form

powder

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H14N5O8P.2Na.H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;;1H2/q;2*+1;/p-2/t3-,5-,6-,9-;;;/m1.../s1

InChI key

MEKWJTZTMVQYSU-CYCLDIHTSA-L

Application

Guanosine 5′-monophosphate is suitable for use in:
  • the measurement of density and viscosity of nucleotide and along with the furanose sugar from 0.0004 to 0.0014mol/kg solution at 288.15, 293.15 and 298.15K at atmospheric pressure
  • the detection and validation of a transcreener assay for detection of AMP- and GMP-producing enzymes
  • the preparation of nucleotide standard during the quantitative profiling of nucleotides using capillary IC-MS/MS

Biochem/physiol Actions

Guanosine 5′-monophosphate (GMP) is a ribonucleoside monophospate which upon phosphorylation to GTP becomes incorporated into ribonucleic acids (RNAs) by various RNA polymerase(s). Guanosine-5′-monophosphate (GMP) can be used to study modulation of glutamatergic neurotransmission.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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