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Merck
CN

G9270

γ-Glutamyltranspeptidase from equine kidney

Type VI, 5-12 units/mg solid

Synonym(s):

γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-931-5
MDL number:
EC Number:
Specific activity:
5-12 units/mg solid
Biological source:
equine kidney
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biological source

equine kidney

Quality Segment

type

Type VI

form

solid

specific activity

5-12 units/mg solid

storage temp.

−20°C

General description

Gamma-Glutamyltranspeptidase is a heterodimeric enzyme and belongs to the superfamily of N-terminal nucleophile hydrolases.

Application

Gamma-glutamyltranspeptidase from equine kidney has been used:

  • to identify the formation of 4-S-Cysteinyltetrodotoxin in the liver of Fugu pardalis
  • as a standard to determine the activity of gamma-glutamyltransferase from human B-cell lymphoma cell lysates
  • to hydrolyze isopeptides to study its effects on tubulin aggregation

Biochem/physiol Actions

Gamma-Glutamyltranspeptidase participates in glutathione metabolism and it catalyzes the cleavage of gamma-glutamyl compounds, such as glutathione. It also plays a role in the transfer of gamma-glutamyl moiety to amino acids and peptides.

Analysis Note

Crude

Other Notes

One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料

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Global Trade Item Number

SKUGTIN
G9270-100UN04061832924243