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G9880

Sigma-Aldrich

Glutamic-Pyruvic Transaminase from porcine heart

ammonium sulfate suspension, ≥75 units/mg protein

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Synonym(s):
L-Alanine: 2-Oxoglutarate Aminotransferase, Alanine Aminotransferase (catalytic concentration), GPT
CAS Number:
9000-86-6
Enzyme Commission number:
2.6.1.2 (BRENDA, IUBMB)
Beilstein:
3562140
EC Number:
232-561-4
MDL number:
MFCD00131192
NACRES:
NA.54

biological source

Porcine heart

Quality Level

200

form

ammonium sulfate suspension

specific activity

≥75 units/mg protein

mol wt

42 kDa

foreign activity

L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%
glutamic-oxalacetic transaminase ≤0.05%

shipped in

wet ice

storage temp.

2-8°C

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Biochem/physiol Actions

Glutamic-pyruvic transaminase (GPT) is located in most cells in the body, but is found in highest concentrations in the liver. It is used as a marker of liver disease due to the release of GPT into the blood following liver cell necrosis.

Unit Definition

One unit will convert 1.0 μmole of α-ketoglutarate to L-glutamate per min at pH 7.6 at 37 °C in the presence of L-alanine.

Physical form

Suspension in 1.8 M (NH4)2SO4 solution, pH 6.0

Analysis Note

Protein determined by biuret.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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