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About This Item
NACRES:
NA.56
UNSPSC Code:
41106500
ligand
quaternary amine
description
Ion Exchanger Type (value)
packaging
pack of 75 mL
manufacturer/tradename
Cytiva 17-1014-01
matrix
6% cross-linked agarose
particle size
24-44 μm
avg. part. size
34 μm
cleaning in place
1-14
working range
2-12
suitability
suitable for bioprocess medium
General description
Q Sepharose High Performance is a strong anion exchange BioProcess resin with high resolution designed for high intermediate and polishing steps in downstream processing.
Q Sepharose High Performance is composed of crosslinked agarose beads with a mean diameter of 34 µm, modified with quaternary (Q) strong anion exchange groups. It is designed for intermediate purification and polishing applications and to be used when resolution and capacity have priority. Q Sepharose High Performance has high chemical stability and withstands effective CIP/sanitization protocols using sodium hydroxide.
Q Sepharose High Performance is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Q Sepharose High Performance meets industrial demands with security of supply and comprehensive technical and regulatory support.
Q Sepharose High Performance is composed of crosslinked agarose beads with a mean diameter of 34 µm, modified with quaternary (Q) strong anion exchange groups. It is designed for intermediate purification and polishing applications and to be used when resolution and capacity have priority. Q Sepharose High Performance has high chemical stability and withstands effective CIP/sanitization protocols using sodium hydroxide.
Q Sepharose High Performance is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Q Sepharose High Performance meets industrial demands with security of supply and comprehensive technical and regulatory support.
Application
Ion Exchange Chromatography (IEX) separates molecules on the bases of differences in their net surface charge. Anion Exchange Chromatography (AIEX) medium interacts with negatively charged proteins and are separated by selective salt elution.
Features and Benefits
- Strong anion exchanger for intermediate and final polishing steps
- High resolution, high capacity separation with high recovery
- High chemical stability for effective CIP/sanitization
- BioProcess resin supported for industrial applications and well-established in approved processes
- The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.
Preparation Note
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Sepharose is a trademark of Cytiva
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Signal Word
Warning
Hazard Codes
Precautionary Statements
Storage Class
3 - Flammable liquids
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