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About This Item
NACRES:
NA.56
UNSPSC Code:
41106500
ligand
quaternary amine
description
Ion Exchanger Type (value)
packaging
pack of 300 mL
manufacturer/tradename
Cytiva 17-5072-01
matrix
6% cross-linked agarose with dextran surface extenders
particle size
45-165 μm
average diameter
90 μm
cleaning in place
2-14
working range
2-12
suitability
suitable for bioprocess medium
General description
Q Sepharose™ XL is a strong anion exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.
Q Sepharose™ XL is based on a highly cross-linked, bead formed 6% agarose matrix similar to the well established Q Sepharose™ Fast Flow media. Dextran chains are covalently coupled to the agarose matrix and modified with quaternary ammonium (Q) strong anion exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates.
With its high loading capacities and excellent physical and chemical stability, Q Sepharose™ XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.
As member of the BioProcess media range, Q Sepharose™ XL meets industrial demands with security of supply and comprehensive technical and regulatory support.
Q Sepharose™ XL is based on a highly cross-linked, bead formed 6% agarose matrix similar to the well established Q Sepharose™ Fast Flow media. Dextran chains are covalently coupled to the agarose matrix and modified with quaternary ammonium (Q) strong anion exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates.
With its high loading capacities and excellent physical and chemical stability, Q Sepharose™ XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.
As member of the BioProcess media range, Q Sepharose™ XL meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
- High loading capacities give more productive capture from clarified feedstocks.
- Strong anion exchanger designed for capture steps
- High chemical stability for effective CIP/sanitization
- The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.
Preparation Note
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Sepharose is a trademark of Cytiva
Signal Word
Warning
Hazard Codes
Precautionary Statements
Storage Class
3 - Flammable liquids
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