GW21143
Anti-AP-1 antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Activator protein 1, Anti-Transcription factor AP-1
biological source
chicken
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human, rat
manufacturer/tradename
Genway 15-288-21143
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... JUN(3725)
Immunogen
Immunogen Sequence: GI # 4758616, sequence 1-240
Recombinant V-jun avian sarcoma virus 17 oncogene homolog
Application
Anti-AP-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
c-Jun is a protein encoded by the JUN gene in humans. c-Jun in combination with c-Fos results in the formation of the AP-1 early response transcription factor. It is crucially involved in propagation of macrophage-driven inflammatory networks. AP1 may guide for the treatment decisions for endometriosis management and may provide a mechanistic endpoint for assessing efficacy of new agents aimed at curtailing inflammatory mechanisms that drive disease progression. It may possibly be utilized for the treatment of HPV-induced cervical cancers.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Juling Lv et al.
International journal of clinical and experimental pathology, 11(8), 4221-4229 (2018-08-01)
Visible light has been previously demonstrated to induce retina damage and retinal ganglion cell (RGC) death through the mitochondrial pathway. The Fra-2 gene was detected as a transcriptional regulator, but whether it is involved in light-induced retina damage remains unclear.
Sutapa Mahata et al.
Nutrition and cancer, 65 Suppl 1, 88-97 (2013-05-25)
Plant products of Phyllanthus emblica Linn. are traditionally consumed for its immense nutritive and medicinal values. However, the molecular mechanism(s) by which it exerts it effects is less understood. In this study, we investigated mechanism of action of P. emblica
Mohamed A Salem et al.
Scientific reports, 12(1), 6578-6578 (2022-04-23)
Aging has become a concern for many people, especially women. Given that high-quality anti-aging products are of high cost; it has imperative to search for other economical sources. Essential oils are frequently used in cosmetics products due to a wide
Michael T Beste et al.
Science translational medicine, 6(222), 222ra16-222ra16 (2014-02-07)
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular profiles of disease activity may improve risk stratification to better inform
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