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Merck
CN

GW21339

Anti-ITGA3 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CD49c, Anti-Integrin α-3, Anti-VL3A

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
5
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biological source

chicken

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat

manufacturer/tradename

Genway 15-288-21339

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGA3(3675)

Immunogen

Immunogen Sequence: GI # 4504747, sequence 1015-1051
Recombinant integrin α 3 isoform a

Application

Anti-ITGA3 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Integrin α-3 is a protein encoded by the ITGA3 gene in humans and is a member of the integrin family of cell adhesion receptors. It is a transmembrane integrin receptor subunit for various laminin isoforms that mediates signals between the cells and their microenvironment. ITGA3 plays an important role in the maintenance of tissue integrity. It may function as a receptor for fibronectin, laminin, and collagen. ITGA3 plays a central role in the interplay of cells, morphogens and ECM and is required for proper nephrogenesis. It acts as a potential marker protein for cells undergoing enhanced Epithelial-mesenchymal transition (EMT) and for cancer cells with aggressive phenotypes.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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