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H0131

DL-4-Hydroxy-3-methoxymandelic acid

Name: <SC>DL</SC>-4-Hydroxy-3-methoxymandelic acid
Brand: SIGMA

≥98% (HPLC), Epinephrine metabolite, powder

Synonym(s):

α,4-Dihydroxy-3-methoxybenzeneacetic acid, VMA, Vanillomandelic acid, Vanillylmandelic acid, Vanilmandelic acid

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About This Item

Linear Formula:

HOC₆H₃(OCH₃)CH(OH)CO₂H

CAS Number:

55-10-7

Molecular Weight:

198.17

NACRES:

NA.77

PubChem Substance ID:

24277743

UNSPSC Code:

12352106

EC Number:

200-224-0

MDL number:

MFCD00004235

Beilstein/REAXYS Number:

2213227

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

200

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Product Name

DL-4-Hydroxy-3-methoxymandelic acid, ≥98% (HPLC), powder

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white to off-white

mp

132-134 °C (dec.) (lit.)

solubility

H₂O: ~50 mg/mL

storage temp.

2-8°C

SMILES string

OC1=C(OC)C=C(C(O)C(O)=O)C=C1

InChI

1S/C9H10O5/c1-14-7-4-5(2-3-6(7)10)8(11)9(12)13/h2-4,8,10-11H,1H3,(H,12,13)

InChI key

CGQCWMIAEPEHNQ-UHFFFAOYSA-N

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Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

Epinephrine and norepineprine metabolite.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Prenatal intrarenal neuroblastoma mimicking a mesoblastic nephroma: a case report.

Sarah Garnier et al.

Journal of pediatric surgery, 47(8), e21-e23 (2012-08-21)

Mesoblastic nephroma is by far the most frequent intrarenal fetal tumor. To the best of our knowledge, we report the first case of a newborn with an intrarenal neuroblastoma that was discovered prenatally. An intrarenal echogenic and homogenous mass was

A single-arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high-risk neuroblastoma.

Wayne L Furman et al.

Investigational new drugs, 30(4), 1660-1670 (2011-07-29)

Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts. This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral gefitinib in children

Adrenal haemangioblastoma presenting as phaeochromocytoma: a rare manifestation of extraneural hemangioblastoma.

Prabal Deb et al.

Endocrine pathology, 23(3), 187-190 (2012-05-01)

Adrenal haemangioblastoma presenting clinically as pheochromocytoma is a rare manifestation of extraneural haemangioblastoma. We present an unusual case of von Hippel-Lindau (VHL) disease that had adrenal and cerebellar haemangioblastoma with multiple renal cysts, and a review of the literature. Unlike

Pheochromocytoma in Indian patients: a retrospective study.

R Krishnappa et al.

Indian journal of cancer, 49(1), 188-193 (2012-07-31)

To review the clinical experience on pheochromocytoma in Indian subset of patients. Ten patients diagnosed with pheochromocytoma between 2001 and 2010 at our institute were retrospectively studied for clinical, laboratory, radiological and surgical data. A total of 10 patients (5

Lack of uniformity in the clinical approach to the interpretation of urinary catecholamines and their metabolites.

W P Tormey et al.

Irish journal of medical science, 164(2), 146-150 (1995-04-01)

A study of the case notes from 101 of the 113 instances where at least one of the results was abnormal from the analysis of 24 hr urinary collections for noradrenaline, adrenaline, and dopamine and their metabolites 4-hydroxy-3-methoxy-mandelic acid (HMMA)

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Global Trade Item Number

SKU	GTIN
H0131-1G	04061833662625
H0131-500MG	04061832082318
H0131-250MG	04061833662632
H0131-100MG	04061833662618
H0131-5G	04061832091051

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