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H1377

4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt

Name: 4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt
Brand: SIGMA

Cerebral norepinephrine metabolite

Synonym(s):

3-Methoxy-4-hydroxy-phenylglycol piperazine, MHPG piperazine, MOPEG, MOPEG piperazine

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₂O₄ · 0.5C₄H₁₀N₂

CAS Number:

67423-45-4

Molecular Weight:

227.26

NACRES:

NA.77

PubChem Substance ID:

24277759

UNSPSC Code:

12352200

EC Number:

266-689-7

MDL number:

MFCD00065957

Beilstein/REAXYS Number:

7360817

Quality level:

200

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Properties

Product Name

4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt,

storage temp.

2-8°C

Quality Level

200

SMILES string

C1CNCCN1.COc2cc(ccc2O)C(O)CO.COc3cc(ccc3O)C(O)CO

InChI

1S/2C9H12O4.C4H10N2/c2*1-13-9-4-6(8(12)5-10)2-3-7(9)11;1-2-6-4-3-5-1/h2*2-4,8,10-12H,5H2,1H3;5-6H,1-4H2

InChI key

KCECBJRHWSOTMR-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Cerebral norepinephrine metabolite.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Effects of U-50,488H and U-50,488H withdrawal on catecholaminergic neurons of the rat hypothalamus.

M L Laorden et al.

Life sciences, 66(9), 803-815 (2000-03-04)

Previous report from our laboratory showed that morphine produces a stimulatory effect of hypothalamic noradrenaline (NA) turnover concurrently with enhanced pituitary-adrenal response after its acute injection and during withdrawal. In the present work we have studied the effects of acute

Variation of monoamines and their metabolite contents in the cerebrospinal fluid of conscious rats.

Y Wada et al.

Japanese journal of pharmacology, 78(2), 237-240 (1998-11-26)

To study the circadian rhythm of the monoamine and metabolite contents, cerebrospinal fluid was taken from the cisterna magna through a polyethylene catheter tube every 4 hr in the conscious rat. Norepinephrine and 3-methoxy-4-hydroxy-phenylglycol were found to describe a rhythm

Simultaneous measurement of monoamines, their metabolites and 2,3- and 2,5-dihydroxybenzoates by high-performance liquid chromatography with electrochemical detection. Application to rat brain dialysates.

J M Duine et al.

Journal of chromatography. B, Biomedical sciences and applications, 716(1-2), 350-353 (1998-11-21)

A reversed-phase chromatographic method with electrochemical detection was developed for the simultaneous determination of 2,3- and 2,5-dihydroxybenzoates, indicators of in vivo hydroxyl free radical formation, monoamines (NE, DA, 5-HT) and their metabolites (MHPG, DOPAC, HVA, 3MT, 5-HIAA). Linearity was observed

Global Trade Item Number

SKU	GTIN
H1377-50MG	04061832082356
H1377-5MG	04061832082363
H1377-25MG	04061833665121
H1377-100MG	04061832091150