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Merck
CN

H1377

4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt

Cerebral norepinephrine metabolite

Synonym(s):

3-Methoxy-4-hydroxy-phenylglycol piperazine, MHPG piperazine, MOPEG, MOPEG piperazine

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About This Item

Empirical Formula (Hill Notation):
C9H12O4 · 0.5C4H10N2
CAS Number:
67423-45-4
Molecular Weight:
227.26
NACRES:
NA.77
PubChem Substance ID:
24277759
UNSPSC Code:
12352200
EC Number:
266-689-7
MDL number:
MFCD00065957
Beilstein/REAXYS Number:
7360817

Key Documents

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Product Name

4-Hydroxy-3-methoxyphenylglycol hemipiperazinium salt,

InChI key

KCECBJRHWSOTMR-UHFFFAOYSA-N

InChI

1S/2C9H12O4.C4H10N2/c2*1-13-9-4-6(8(12)5-10)2-3-7(9)11;1-2-6-4-3-5-1/h2*2-4,8,10-12H,5H2,1H3;5-6H,1-4H2

SMILES string

C1CNCCN1.COc2cc(ccc2O)C(O)CO.COc3cc(ccc3O)C(O)CO

storage temp.

2-8°C

Quality Level

200

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Related Categories

Biochem/physiol Actions

Cerebral norepinephrine metabolite.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF8951
BCBV9317
BCBP7147
BCBP7147V
BCBN6227

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Y Wada et al.
Japanese journal of pharmacology, 78(2), 237-240 (1998-11-26)
To study the circadian rhythm of the monoamine and metabolite contents, cerebrospinal fluid was taken from the cisterna magna through a polyethylene catheter tube every 4 hr in the conscious rat. Norepinephrine and 3-methoxy-4-hydroxy-phenylglycol were found to describe a rhythm
M L Laorden et al.
Life sciences, 66(9), 803-815 (2000-03-04)
Previous report from our laboratory showed that morphine produces a stimulatory effect of hypothalamic noradrenaline (NA) turnover concurrently with enhanced pituitary-adrenal response after its acute injection and during withdrawal. In the present work we have studied the effects of acute
J M Duine et al.
Journal of chromatography. B, Biomedical sciences and applications, 716(1-2), 350-353 (1998-11-21)
A reversed-phase chromatographic method with electrochemical detection was developed for the simultaneous determination of 2,3- and 2,5-dihydroxybenzoates, indicators of in vivo hydroxyl free radical formation, monoamines (NE, DA, 5-HT) and their metabolites (MHPG, DOPAC, HVA, 3MT, 5-HIAA). Linearity was observed

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