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H1791

Anti-HOXC8 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-HOX3A, Anti-Homeobox 3A, Anti-Homeobox C8, Anti-Hox-3.1 (mouse)

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
6
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~34 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

immunoprecipitation (IP): 2.5-5 μg using lysates of HEK-293T cells over expressing human HOXC8, western blot: 1-2 μg/mL using extracts of HEK-293T cells over expressing human HOXC8

UniProt accession no.

P31273

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HOXC8(3224)
mouse ... Hoxc8(15426)
rat ... Hoxc8(24460)

General description

Homeobox C8 (HOXC8) is a member of homeobox (HOX) family. It is a transcription factor, expressed in neural tube, brain, breast and adult bone marrow. HOX genes consist of a highly conserved 60-amino-acid region (the homeobox) with DNA-binding activity, that contributes to their activity as transcription factors. The gene is located on human chromosome 12q13.

Immunogen

synthetic peptide corresponding to amino acids 96-110 of human HOXC8 conjugated to KLH. The corresponding sequence is identical in mouse and rat.

Application

Anti-HOXC8 antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

Homeobox C8 (HOXC8) is involved in cell growth, migration and metastasis of various cancers. Hox genes are important for embryonic development. Mutations in this gene are implicated in the development of cancers, such as leukemias or neoplasms of the breast, prostate, kidney, colon, skin and brain.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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