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Merck
CN

H2255

5-Hydroxyindole-3-acetic acid (dicyclohexylammonium) salt

crystalline, ≥98% (TLC)

Synonym(s):

5-HIAA

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About This Item

Empirical Formula (Hill Notation):
C10H9NO3 · C12H23N
CAS Number:
Molecular Weight:
372.50
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C12H23N.C10H9NO3/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h11-13H,1-10H2;1-2,4-5,11-12H,3H2,(H,13,14)

SMILES string

C1CCC(CC1)NC2CCCCC2.OC(=O)Cc3c[nH]c4ccc(O)cc34

InChI key

NIDSGTAJKGNSEN-UHFFFAOYSA-N

assay

≥98% (TLC)

form

crystalline

color

white

storage temp.

−20°C

Biochem/physiol Actions

Major serotonin metabolite.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Jurjen J Luykx et al.
PloS one, 7(2), e30497-e30497 (2012-02-09)
Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal patterns in CSF MA turnover in a large set of healthy adults. Standardized amounts of CSF were prospectively collected
ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation.
U Knigge et al.
Neuroendocrinology, 105(3), 310-319 (2017-02-22)
Christian Pifl et al.
Frontiers in neuroanatomy, 11, 46-46 (2017-06-15)
Parkinson's disease (PD) is a neurodegenerative disease with both motor and non-motor manifestations. Hyposmia is one of the early non-motor symptoms, which can precede motor symptoms by several years. The relationship between hyposmia and PD remains elusive. Olfactory bulb (OB)
Juliet McColm et al.
British journal of clinical pharmacology, 83(8), 1654-1667 (2017-02-06)
The safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of single and multiple doses of a novel mGlu2 agonist were assessed in healthy males. In two, Phase 1 investigator- and subject-blind, placebo-controlled studies, oral doses of prodrug LY2979165 were evaluated: single doses
Xue Tao et al.
International journal of molecular sciences, 21(4) (2020-02-27)
In the pathology-oriented study of depression, inflammation hypothesis has received increasing attention for recent years. To mimic the depressive state caused by inflammation, rodents injected intraperitoneally with lipopolysaccharide (LPS) are usually used to stimulate an immune response. However, the dose

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