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Merck
CN

H2270

Hydrocortisone 21-hemisuccinate sodium salt

powder, BioReagent, suitable for cell culture

Synonym(s):

11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt, Cortisol 21-hemisuccinate sodium salt

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About This Item

Empirical Formula (Hill Notation):
C25H33NaO8
CAS Number:
125-04-2
Molecular Weight:
484.51
NACRES:
NA.77
PubChem Substance ID:
24278463
UNSPSC Code:
12352209
EC Number:
204-725-5
MDL number:
MFCD00069472
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥90% (HPLC)

Key Documents

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Product Name

Hydrocortisone 21-hemisuccinate sodium salt, powder, BioReagent, suitable for cell culture

InChI key

HHZQLQREDATOBM-CODXZCKSSA-M

InChI

1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

SMILES string

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]

biological source

synthetic (organic)

product line

BioReagent

assay

≥90% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

200

Gene Information

human ... NR3C1(2908)

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Application

Hydrocortisone 21-hemisuccinate sodium salt has been used as a supplement in Dulbecco′s modified Eagle medium/nutrient mixture F-12 (DMEM F12) for culturing oral squamous cell carcinoma (OSCC) cell lines and immortalized cone photoreceptor cell line.

General description

Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361d

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000475817
0000475817
0000436527
0000436527
0000422276

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