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Merck
CN

H3647

Methyl 4-hydroxybenzoate

BioReagent, suitable for insect cell culture

Synonym(s):

p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:
HOC6H4CO2CH3
CAS Number:
99-76-3
Molecular Weight:
152.15
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
24895585
EC Number:
202-785-7
Beilstein/REAXYS Number:
509801
MDL number:
MFCD00002352

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InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

SMILES string

COC(=O)c1ccc(O)cc1

biological source

synthetic

product line

BioReagent

assay

≥99.0% (HPLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable

Quality Level

200

Gene Information

rat ... Ar(24208)

solubility

ethanol: 50 mg/mL, clear, colorless

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General description

Parabens are ester derivatives of hydroxybenzoic acid. Methyl 4-hydroxybenzoate is a short-chain paraben, suitable for applications in food. It is found in cloudberry, white wine, yellow passion fruit, and bourbon vanilla.

Application

Methyl 4-hydroxybenzoate has been used:
  • to wash mites from the cells of Apis mellifera workers preceding the harvest of mite saliva
  • as a component of grape/apple juice agar plates to culture Drosophila for the extraction of ovaries/embryos
  • in studies on sterol hormones such as testosterone biosynthesis

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3361
0000454512
0000454512
SLCN3713
0000454510

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Yi Zhang et al.
Journal of economic entomology, 112(2), 505-514 (2018-09-17)
The Varroa destructor (Acari Varroidae) mite is a serious threat to honey bee due to hemolymph feeding and virus transmission. Mite salivary proteins are involved in these interactions. However, the salivary secretome has not been previously characterized. In this paper
Iliana Correa et al.
STAR protocols, 2(2), 100592-100592 (2021-06-26)
We have outlined the approach of visualizing autophagy specifically in the epithelial follicle stem cells of the Drosophila ovary using the LysoTracker dye. The advantage of using this protocol is that it details several techniques, including ovary dissection, immunofluorescence, and
Preservatives: Food Use
Garcia RG, et al.
Encyclopedia of Food and Health, 505-509 (2016)
Ivo A Telley et al.
Nature protocols, 8(2), 310-324 (2013-01-19)
Spindle assembly and chromosome segregation rely on a complex interplay of biochemical and mechanical processes. Analysis of this interplay requires precise manipulation of endogenous cellular components and high-resolution visualization. Here we provide a protocol for generating an extract from individual
Mousumee Khan et al.
Nutrients, 11(5) (2019-05-01)
Resveratrol has gained widespread scientific attention due to its ability to significantly extend the lifespan of yeast. However, research on the efficacy of resveratrol on lifespan extension has yielded mixed results in animal studies, making resveratrol a contentious subject. In
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