H3884
Hyaluronidase from bovine testes
Type IV-S, lyophilized powder (essentially salt-free), 750-3000 units/mg solid
biological source
bovine testis
Quality Level
conjugate
conjugate (Glucosaminoglycan)
type
Type IV-S
form
lyophilized powder (essentially salt-free)
specific activity
750-3000 units/mg solid
mol wt
~55 kDa (four subunits of 14 kDa each)
application(s)
diagnostic assay manufacturing
relevant disease(s)
cancer
storage temp.
−20°C
Gene Information
cow ... HYAL1(515397) , HYAL2(281838)
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Related Categories
Biochem/physiol Actions
Unit Definition
Other Notes
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
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Can stock solutions of Product H3884, Hyaluronidase from bovine testes, be stored frozen after reconstitution?
Although Sigma-Aldrich has not tested the stability of stock solutions of Product H3884, Hyaluronidase from bovine testes, several publications cite storage of solutions of H3884 at -20 °C:1. Campbell, Keith H.S, "Transgenic Sheep form Cultured Cells", from Transgenesis Techniques: Principles and Protocols, Methods Mol. Biol., 180, 289-301 (2002). A 1500 IU/mL stock solution was stored in 20 mL aliquots at -20 °C.2. Marschall, S. and de Angelis, M.H., "In Vitro Fertilization/Cryopreservation", from Transgenic Mouse: Methods and Protocols, Methods in Molecular Biology, 209, pp. 35-50. Humana Press (2003). 1 mg/mL stock solutions in M2 medium or water, sterile-filtered (0.22 mm filter) can be stored in aliquots at -20 °C.
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Articles
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
Protocols
This procedure may be used for Hyaluronidase products.
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