H4002
DL-3-Hydroxynorvaline
≥98% (TLC)
Synonym(s):
HNV, α-Amino-β-hydroxyvaleric acid, 2-Amino-3-hydroxypentanoic acid, 3-Hydroxy-2-aminopentanoic acid, DL-β-Hydroxynorvaline
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About This Item
Empirical Formula (Hill Notation):
C5H11NO3
CAS Number:
Molecular Weight:
133.15
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
1722350
MDL number:
Product Name
DL-3-Hydroxynorvaline, ≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
form
powder
color
white
application(s)
cell analysis
storage temp.
−20°C
SMILES string
CCC(O)C(N)C(O)=O
InChI
1S/C5H11NO3/c1-2-3(7)4(6)5(8)9/h3-4,7H,2,6H2,1H3,(H,8,9)
InChI key
LGVJIYCMHMKTPB-UHFFFAOYSA-N
Biochem/physiol Actions
3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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