H4024
L-Homocysteinesulfinic acid
≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C4H9NO4S
CAS Number:
Molecular Weight:
167.18
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
InChI
1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)
SMILES string
NC(CCS(O)=O)C(O)=O
InChI key
PDNJLMZEGXHSCU-UHFFFAOYSA-N
assay
≥98% (TLC)
storage temp.
−20°C
Biochem/physiol Actions
Neurotransmitter candidate
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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M Bouvier et al.
The Journal of physiology, 444, 441-457 (1991-12-01)
1. The effect of sulphur-containing analogues of glutamate and aspartate on the membrane current of glial cells was studied by whole-cell clamping Müller cells isolated from the salamander retina. 2. L-Cysteic acid (CA), L-cysteinesulphinic acid (CSA), L-homocysteic acid (HCA), L-homocysteinesulphinic
Homocysteic acid, an endogenous agonist of NMDA-receptor: release, neuroactivity and localization.
M Cuénod et al.
Advances in experimental medicine and biology, 203, 253-262 (1986-01-01)
H Sugiyama et al.
Neuron, 3(1), 129-132 (1989-07-01)
Three major subtypes of glutamate receptors that are coupled to cation channels are known. Recently an additional subtype that is coupled to G proteins and stimulates inositol phospholipid metabolism (the metabotropic glutamate receptor) has been proposed. The pharmacological characteristics of
Angelina Y Fong et al.
Journal of neurophysiology, 99(2), 900-914 (2007-12-07)
We studied the role of neurokinin-1 receptors (NK1-R) on the excitability of expiratory (E) neurons (tonic discharge, E(TONIC); augmenting, E(AUG); decrementing, E(DEC)) throughout the ventral respiratory group, including Bötzinger Complex (BötC) using extracellular single-unit recording combined with pressurized picoejection in
L-homocysteine sulfinic acid and L-homocysteic acid stimulate phosphoinositide hydrolysis in rat cortical neurons.
Qi Shi et al.
Annals of the New York Academy of Sciences, 1003, 461-463 (2003-12-20)
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