H4024
L-Homocysteinesulfinic acid
≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C4H9NO4S
CAS Number:
Molecular Weight:
167.18
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
Assay
≥98% (TLC)
storage temp.
−20°C
SMILES string
NC(CCS(O)=O)C(O)=O
InChI
1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)
InChI key
PDNJLMZEGXHSCU-UHFFFAOYSA-N
Biochem/physiol Actions
Neurotransmitter candidate
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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M Bouvier et al.
The Journal of physiology, 444, 441-457 (1991-12-01)
1. The effect of sulphur-containing analogues of glutamate and aspartate on the membrane current of glial cells was studied by whole-cell clamping Müller cells isolated from the salamander retina. 2. L-Cysteic acid (CA), L-cysteinesulphinic acid (CSA), L-homocysteic acid (HCA), L-homocysteinesulphinic
Homocysteic acid, an endogenous agonist of NMDA-receptor: release, neuroactivity and localization.
M Cuénod et al.
Advances in experimental medicine and biology, 203, 253-262 (1986-01-01)
H Sugiyama et al.
Neuron, 3(1), 129-132 (1989-07-01)
Three major subtypes of glutamate receptors that are coupled to cation channels are known. Recently an additional subtype that is coupled to G proteins and stimulates inositol phospholipid metabolism (the metabotropic glutamate receptor) has been proposed. The pharmacological characteristics of
Angelina Y Fong et al.
Journal of neurophysiology, 99(2), 900-914 (2007-12-07)
We studied the role of neurokinin-1 receptors (NK1-R) on the excitability of expiratory (E) neurons (tonic discharge, E(TONIC); augmenting, E(AUG); decrementing, E(DEC)) throughout the ventral respiratory group, including Bötzinger Complex (BötC) using extracellular single-unit recording combined with pressurized picoejection in
C R Santhosh-Kumar et al.
Analytical biochemistry, 220(2), 249-256 (1994-08-01)
Oxidized sulfur-containing amino acids are recognized as agonists of excitatory amino acid receptors in the mammalian nervous system. Homologues of glutamic acid (homocysteine sulfinic acid and homocysteic acid) and aspartic acid (cysteine sulfinic acid and cysteic acid) have been shown
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