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H4644

Hypercalcemia of malignancy factor 1-40 human

≥95% (HPLC), suitable fo drug transporter assays

Synonym(s):

Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser, PTH-Like Adenylate Cyclase Stimulating Protein, PTHrP (1-40), Parathyroid hormone-related protein (1-40)

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About This Item

Empirical Formula (Hill Notation):
C207H334N66O58
CAS Number:
120298-73-9
Molecular Weight:
4675.27
UNSPSC Code:
12352201
NACRES:
NA.26
MDL number:
MFCD00081712
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Product Name

Hypercalcemia of malignancy factor 1-40 human, ≥95% (HPLC)

Quality Level

200

assay

≥95% (HPLC)

form

solid

technique(s)

drug transporter assay: suitable

UniProt accession no.

P12272

storage temp.

−20°C

Gene Information

human ... PTHLH(5744)

Biochem/physiol Actions

Hypercalcemia of malignancy factor fragment 1-40 human is a parathyroid hormone-like protein (PLP) fragment used to study parathyroid hormone-related signaling pathways.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000490833
0000490833
0000488464
0000488464
0000471811

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Parathyroid hormone-related peptide and primary hyperparathyroidism.
Testini M, Gurrado A, et al.
Frontiers in Bioscience, 2, 299-312 (2010)
C Cataisson et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 15(11), 2129-2139 (2000-11-25)
Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as well as breast cancer tumors and cell lines have been reported as
J M Moseley et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(14), 5048-5052 (1987-07-01)
A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major protein band of 18 kDa was obtained on NaDodSO4/polyacrylamide gels, with faint
View All Related Papers

Global Trade Item Number

SKUGTIN
H4644-.1MG04061832820606