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H5777

(±)-Huperzine A

synthetic, ≥98% (TLC)

Synonym(s):

(±)-Selagine

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About This Item

Empirical Formula (Hill Notation):
C15H18N2O
CAS Number:
120786-18-7
Molecular Weight:
242.32
NACRES:
NA.77
PubChem Substance ID:
24895708
UNSPSC Code:
12352200
MDL number:
MFCD00171439
Assay:
≥98% (TLC)
Form:
powder
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Quality Segment

biological source

synthetic

assay

≥98% (TLC)

form

powder

solubility

methanol: 10 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

C\C=C1/C2CC3=C(C=CC(=O)N3)C1(N)CC(C)=C2

InChI

1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+

InChI key

ZRJBHWIHUMBLCN-QDEBKDIKSA-N

Gene Information

human ... BCHE(590)
rat ... Ache(83817)

General description

Huperzine A is an alkaloid derived from Chinese club moss Huperzia serrata.

Application

(±)-Huperzine A has been used in anti-acetylcholinesterase bioautographic assay.

Biochem/physiol Actions

Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.

Features and Benefits

Acetylcholinesterase inhibitor.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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