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H6501

DL-β-Hydroxybutyric acid sodium salt

Name: <SC>DL</SC>-&#946;-Hydroxybutyric acid sodium salt
Brand: SIGMA

~98%, powder

Synonym(s):

(±)-3-Hydroxybutanoic acid sodium salt

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About This Item

Linear Formula:

C₄H₇O₃Na

CAS Number:

150-83-4

Molecular Weight:

126.09

NACRES:

NA.83

PubChem Substance ID:

24895744

UNSPSC Code:

12352204

EC Number:

205-774-5

MDL number:

MFCD00016716

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Properties

Product Name

DL-β-Hydroxybutyric acid sodium salt, ~98%

assay

~98%

Quality Segment

200

form

powder

solubility

water: 1 g/10 mL, clear, colorless

storage temp.

2-8°C

SMILES string

[Na].CC(O)CC(O)=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

Description

Application

DL-β-Hydroxybutyric acid sodium salt has been used:

as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
to investigate its anticonvulsant effects in epilepsy induced rats
to induce hyperketonemia in Holstein dairy cows

Biochem/physiol Actions

β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD⁺, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品

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Global Trade Item Number

SKU	GTIN
H6501-5G	04061833800966
H6501-25G	04061833057827
H6501-100G	04061833057810