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H8892

Heparin disaccharide I-H sodium salt

Synonym(s):

α-ΔUA-2S-[1→4]-GlcN-6S

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About This Item

Linear Formula:
C12H17NO16S2Na2
CAS Number:
136098-04-9
Molecular Weight:
541.37
NACRES:
NA.25
PubChem Substance ID:
329815254
UNSPSC Code:
12352201
MDL number:
MFCD00466926
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assay

~99% (HPLC)

form

solid

technique(s)

HPLC: suitable

color

white to faint yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2OC(=C[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@@H]1O

InChI

1S/C12H19NO16S2.3Na/c13-6-7(15)9(5(26-11(6)18)2-25-30(19,20)21)28-12-8(29-31(22,23)24)3(14)1-4(27-12)10(16)17;;;/h1,3,5-9,11-12,14-15,18H,2,13H2,(H,16,17)(H,19,20,21)(H,22,23,24);;;/q;3*+1/p-3/t3-,5+,6+,7+,8+,9+,11?,12-;;;/m0.../s1

InChI key

WHYGSGRAJJCXLY-LXROVJCJSA-K

Application

Heparin disaccharide I-H sodium salt has been used as a non-naphthalene, negatively charged, bivalent compound to test its ability to induce liquid-liquid phase separation (LLPS).

Biochem/physiol Actions

Heparin disaccharide is a bivalent compound with less hydrophobic nature. It elevates the cytosolic calcium (Ca2+) extrusion rate and may serve as a potential drug for the activation of Na+ /Ca2+ exchanger (NCX).
Products of the digestion of heparin and heparan sulfate by various heparinases

Other Notes

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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