H8909
HBcAg core human
~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
Synonym(s):
Hepatitis B virus core antigen
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About This Item
recombinant
expressed in E. coli
Quality Segment
assay
≥95% (SDS-PAGE)
mol wt
18 kDa
concentration
~1 mg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
hepatitis B virus ... HBVgp4(944568)
human ... HBVgp4(944568)
General description
amino acids 1-183 of HBV core antigen.
Biochem/physiol Actions
HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.
Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.
Physical form
Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
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Datasheet
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H8909-100UG | 04061838071262 |