I0281
Interleukin-4/Fc Chimera (non-lytic) from mouse
>98% (SDS-PAGE), recombinant, expressed in CHO cells, buffered aqueous solution
Synonym(s):
IL-4:Fc (non-lytic)
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About This Item
biological source
mouse
recombinant
expressed in CHO cells
assay
>98% (SDS-PAGE)
form
buffered aqueous solution
mol wt
98 kDa
packaging
pkg of 10 μg
impurities
endotoxin, tested
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il4(16189)
Biochem/physiol Actions
In mice, absence of IL-4 (interleukin-4) causes anxiety-like behavior. It is secreted by Th2 (T helper) cells and works as a pro-inflammatory cytokine. It plays an important role in immune response and allergic diseases. It is also associated with schistosoma mansoni pulmonary hypertension.
Possesses the biological functions of the IL-4 moiety and a prolonged circulating half-life determined by the Fc domain.
Physical form
Solution in 0.2 μm filtered phosphate buffered saline, pH 7.4.
Other Notes
Dimeric fusion protein consisting of mouse IL-4 fused to mutant mouse Fcγ2a Fc.
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