I0531
Interleukin-18 from rat
>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
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About This Item
biological source
rat
Quality Segment
recombinant
expressed in E. coli
assay
>97% (SDS-PAGE)
form
lyophilized powder
potency
10-60 ng/mL ED50
mol wt
predicted mol wt ~18.4 kDa
packaging
pkg of 25 μg
impurities
endotoxin, tested
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
rat ... Il18(29197)
Biochem/physiol Actions
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
Physical form
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
Analysis Note
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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