6-(Iodoacetamido)hexanoic acid N-hydroxysuccinimide ester

Name: 6-(Iodoacetamido)hexanoic acid N-hydroxysuccinimide ester
Brand: SIGMA

powder

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₇IN₂O₅

CAS Number:

134759-23-2

Molecular Weight:

396.18

UNSPSC Code:

12171500

MDL number:

MFCD00132999

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Properties

form

powder

solubility

methanol: 50 mg/mL, DMF: soluble

storage temp.

−20°C

SMILES string

ICC(=O)NCCCCCC(=O)ON1C(=O)CCC1=O

Description

Application

A heterobifunctional cross-linking reagent containing an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 9-atom linker.

Disclaimer

The iodoacetyl group is light sensitive.

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