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About This Item
Conjugate:
unconjugated
Species reactivity:
-
Application:
—
Citations:
22
conjugate
unconjugated
Quality Level
grade
reagent grade
assay
≥95%
form
essentially salt-free, lyophilized powder
storage temp.
2-8°C
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General description
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.
Application
Purified IgA may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, immunoblotting, immunodiffusion and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solidphase immunoadsorbents. IgA from human colostrum was used as a standard in ELISA (1 mg/ml) and gel electrophoresis.
Preparation Note
Reconstitute with buffered saline (150 mM sodium chloride).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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P Kosuwon et al.
Beneficial microbes, 9(4), 541-552 (2018-04-11)
Little is known about the impact of nutrition on toddler gut microbiota. The plasticity of the toddler gut microbiota indicates that nutritional modulation beyond infancy could potentially impact its maturation. The objective of this study was to determine the effect
Hannah Karen Mina Labayo et al.
EClinicalMedicine, 27, 100561-100561 (2020-10-13)
Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diarrhea is still unknown. This study aimed
E Knop et al.
Investigative ophthalmology & visual science, 42(3), 566-574 (2001-02-27)
Mucosa-associated lymphoid tissue (MALT) specifically protects mucosal surfaces. In a previous study of the human conjunctiva, evidence was also found for the presence of MALT in the lacrimal sac. The present study, therefore, aims to investigate its morphology and topographical
Nguyen V Trang et al.
Human vaccines & immunotherapeutics, 10(12), 3681-3687 (2015-02-11)
Rotavirus (RV) is the most common cause of childhood diarrhea worldwide, and several vaccines have been successfully developed to reduce the burden of disease. However, lower vaccine immunogenicity and efficacy in developing countries might be related to the virus-neutralizing activity
Lloyd S Robinson et al.
The Journal of biological chemistry, 294(14), 5230-5245 (2019-02-07)
Gardnerella vaginalis is abundant in bacterial vaginosis (BV), a condition associated with adverse reproductive health. Sialidase activity is a diagnostic feature of BV and is produced by a subset of G. vaginalis strains. Although its genetic basis has not been
Related Content
Instructions
Global Trade Item Number
| SKU | GTIN |
|---|---|
| I1010-5MG | 04061833847381 |
| I1010-25MG | 04061833847374 |
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