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I1877

Isocitric Dehydrogenase (NADP) from porcine heart

Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)

Synonym(s):

threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH

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About This Item

CAS Number:
9028-48-2
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-835-3
MDL number:
MFCD00131420
EC Number:
1.1.1.42 (BRENDA, IUBMB)
Specific activity:
0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)
Biological source:
Porcine heart

Key Documents

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Product Name

Isocitric Dehydrogenase (NADP) from porcine heart, Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)

biological source

Porcine heart

type

Type I

form

solid

specific activity

0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)

storage temp.

−20°C

Quality Level

200

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Analysis Note

Crude

Biochem/physiol Actions

Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers.

Other Notes

One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H334

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料
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Certificates of Analysis (COA)

Lot/Batch Number
0000504164
0000504164
SLBC6000V
SLBD5673V
081K7069

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