I2393
IL-1β rat
≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym(s):
IL-1β, Interleukin-1β from rat, Lymphocyte activating factor
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About This Item
Biological source:
rat
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE and HPLC)
Form:
lyophilized powder
Mol wt:
17.3 kDa
Impurities:
<0.1 EU/μg
Product Name
Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
rat
Quality Segment
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE and HPLC)
form
lyophilized powder
potency
0.01-0.1 ng/mL ED50/EC50
mol wt
17.3 kDa
packaging
pkg of 10 and 50 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Il1b(24494)
General description
Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin-2.1 IL-1 is primarily released from stimulated macrophages and monocytes, but is also released from several other cell types,2 and is thought to play a key role in inflammatory and immune responses.3 Other synonyms for IL-1 include: Endogenous Pyrogen (EP), Mitogenic Protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFH), B cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF).4 The two closely related agents, Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) bind to the same cell surface receptor, elicit nearly identical biological responses and yet share 25% homology in their amino acid sequence. Recombinant rat IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
Physical form
Lyophilized from a 0.2 μm filtered buffered solution.
Analysis Note
The biological activity is measured in a cell proliferation assay using murine D10S cells.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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