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About This Item
Biological source:
rat
Recombinant:
expressed in E. coli
Assay:
≥97% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
~18 kDa
Impurities:
≤0.1 EU/μg
Product Name
Interleukin-1α from rat, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
rat
Quality Segment
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
1-10 pg/mL ED50
quality
endotoxin tested
mol wt
~18 kDa
packaging
pkg of 5 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤0.1 EU/μg
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Il1a(24493)
General description
Recombinant Interleukin‑1α from rat (IL‑1α) is expressed in Escherichia coli and supplied as a lyophilized powder. IL‑1α is a pro‑inflammatory cytokine commonly used in mammalian cell culture research to study immune‑related cellular responses in vitro.
Application
Recombinant rat IL‑1α has been used in mammalian cell culture research applications, including lymphocyte activation studies and cytokine‑mediated signaling assays in vitro.
Biochem/physiol Actions
Interleukin‑1α (IL‑1α) is an immunomodulatory cytokine that mediates activation and proliferation of immune cell populations in vitro. Recombinant rat IL‑1α has been widely studied in cell‑based models investigating cytokine‑driven immune signaling pathways.
Physical form
Lyophilized from 0.2 μm filtered phosphate buffered saline containing 0.25 mg of bovine serum albumin.
Analysis Note
The biological activity of recombinant rat IL-1α was measured by its ability to stimulate cell proliferation using a mouse helper T cell line, D10.G4.1.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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