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I7003

Ibogaine hydrochloride

Name: Ibogaine hydrochloride
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₂₆N₂O · HCl

CAS Number:

5934-55-4

Molecular Weight:

346.89

UNSPSC Code:

12352200

EC Number:

227-687-1

MDL number:

MFCD00167426

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Properties

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

H₂O: soluble, methanol: soluble

application(s)

forensics and toxicology

SMILES string

Cl.CCC1CC2CC3C1N(CCc4c3[nH]c5ccc(OC)cc45)C2

Description

Biochem/physiol Actions

CNS stimulant and hallucinogen; anti-convulsant.

Ibogaine is a central nervous system stimulant and hallucinogen that has been reported to be a σ₂ agonist, a noncompetitive NMDA receptor antagonist at the phencyclidine site and an enhancer of purinergic muscle contractions. It is also a competitive inhibitor of serotonin and dopamine transport. It is an anti-convulsant and has anti-addictive properties against cocaine and heroin.

Preparation Note

Alkaloid isolated from the African shrub, Tabernanthe iboga.

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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