I7634
D-Isoleucine
≥98% (TLC)
Synonym(s):
(2R, 3R)-2-Amino-3-methylpentanoic acid
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About This Item
Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-269-2
MDL number:
Product Name
D-Isoleucine, ≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
form
powder
impurities
≤10% allo-isomer
color
white
application(s)
cell analysis
SMILES string
CC[C@@H](C)[C@@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1
InChI key
AGPKZVBTJJNPAG-RFZPGFLSSA-N
Application
- Metabolic Profiling of Urinary Chiral Amino-Containing Biomarkers for Gastric Cancer Using a Sensitive Chiral Chlorine-Labeled Probe by HPLC-MS/MS.: This study by Huang et al. (2021) explores the use of D-Isoleucine as a biomarker for gastric cancer, utilizing advanced metabolic profiling techniques with HPLC-MS/MS to detect chiral amino-containing compounds in urine samples (Huang et al., 2021).
- Isopenicillin N Synthase Binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine Through Both Sulfur Atoms.: Clifton et al. (2011) describe the binding mechanism of Isopenicillin N synthase with a compound involving D-Isoleucine, highlighting its role in antibiotic biosynthesis and enzyme interaction studies (Clifton et al., 2011).
- The Total Structure of the Antibiotic Longicatenamycin.: Shiba and Mukunoki (1975) determined the complete structure of the antibiotic longicatenamycin, which includes D-Isoleucine as a crucial component, contributing to understanding its antibacterial properties (Shiba and Mukunoki, 1975).
Biochem/physiol Actions
D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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