I9135
Anti-Human IgG (Fc specific) antibody produced in rabbit
whole antiserum
Synonym(s):
Human Antiserum, Rabbit Anti Human IgG - Anti-Human IgG (Fc specific) antibody produced in rabbit, Rabbit Anti Human Igg, Rabbit Antiserum
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), QPA
Citations:
9
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
secondary antibodies
clone
polyclonal
contains
15 mM sodium azide
technique(s)
indirect ELISA: 1:100,000, quantitative precipitin assay: 1.5 mg/mL
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
IgG contains four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, that are associated by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.
Application
Anti-Human IgG (Fc specific) antibody produced in rabbit was used in immunoblotting and immunocytochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Biochem/physiol Actions
IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a pivotal role in antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis. It might be linked to allergy and has the longest serum half life.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Preparation Note
treated to remove lipoproteins
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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