I9659
Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse
clone 75014, purified immunoglobulin, lyophilized powder
Synonym(s):
Anti-IGF2, Anti-INSIGF
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About This Item
Conjugate:
unconjugated
Clone:
75014, monoclonal
Application:
WB
Citations:
4
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
75014, monoclonal
form
lyophilized powder
species reactivity
human
technique(s)
western blot: 1-2 μg/mL
isotype
IgG2a
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IGF2(3481)
Immunogen
purified, E. coli-derived recombinant human insulin-like growth factor-II.
Biochem/physiol Actions
Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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