I9784
Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse
clone 75015, purified immunoglobulin, lyophilized powder
Synonym(s):
Anti-IGF2, Anti-INSIGF
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About This Item
Conjugate:
unconjugated
Clone:
75015, monoclonal
Application:
Neutral
Citations:
4
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
75015, monoclonal
form
lyophilized powder
species reactivity
human
technique(s)
neutralization: suitable
isotype
IgG1
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... IGF2(3481)
Immunogen
purified, E. coli-derived recombinant human insulin-like growth factor-II.
Biochem/physiol Actions
Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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