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Merck
CN

I9885

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Goat Anti-Human IgG

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162442

Key Documents

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Product Name

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment antibody produced in goat, affinity isolated antibody, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

lyophilized powder

packaging

pkg of 5x1 mg
pkg of 1 mg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

Ouchterlony double diffusion: suitable
quantitative precipitin assay: suitable

color

white to off-white

solubility

water: soluble, clear to hazy, colorless (after reconstitution with 1 ml of 0.135 M NaCl)

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

200

Related Categories

Application

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment antibody is suitable for Ouchterlony double diffusion and quantitative precipitin assay. The antibody was used in ELISA and to produce Fab′-oligonucleotide conjugates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. Anti-Human IgG (γ-chain specific), F(ab′)2 fragment antibody is specific for human IgG subclasses. The F(ab′)2 fragment of the antibody is obtained from pepsin-digested antiserum by immunospecific methods of purification.

Immunogen

Purified human IgG

Physical form

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品
常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
0000260105
0000260105
SLCN2818
SLCG8718
SLCF3734

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Hiroyasu Muramatsu et al.
Scientific reports, 11(1), 2160-2160 (2021-01-27)
Myostatin, a member of the transforming growth factor-β superfamily, is an attractive target for muscle disease therapy because of its role as a negative regulator of muscle growth and strength. Here, we describe a novel antibody therapeutic approach that maximizes
Z N Chaudri et al.
FEBS letters, 450(1-2), 23-26 (1999-06-01)
The covalent conjugation of oligonucleotides to antibody Fab' fragments was optimized by using oligonucleotides modified with a hexaethylene linker arm bearing three amino groups. One oligonucleotide was coupled to antibody of one specificity and a complementary oligonucleotide to antibody of
H Brandstätter et al.
Vox sanguinis, 103(3), 201-212 (2012-04-14)
Complement factor H (CFH) acts as major regulator of the alternative pathway of complement and its mutations and polymorphisms predispose to various human diseases. We aimed to develop a scalable purification process of CFH from human plasma fractions to supply
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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Data Sheet - I9885

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