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K113

Ketamine hydrochloride/xylazine hydrochloride solution

Name: Ketamine hydrochloride/xylazine hydrochloride solution
Brand: SIGMA

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About This Item

CAS Number:

61763-23-3

NACRES:

NA.77

PubChem Substance ID:

329817124

UNSPSC Code:

12352116

MDL number:

MFCD00798875

Form:

solution

Quality level:

200

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form

solution

Quality Level

200

drug control

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

color

colorless

storage temp.

2-8°C

SMILES string

Cl.Cl.Cc1cccc(C)c1NC2=NCCCS2.CNC3(CCCCC3=O)c4ccccc4Cl

InChI

1S/C13H16ClNO.C12H16N2S.2ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;;/h2-3,6-7,15H,4-5,8-9H2,1H3;3,5-6H,4,7-8H2,1-2H3,(H,13,14);2*1H

InChI key

IYJHJWJNWIPQFJ-UHFFFAOYSA-N

Biochem/physiol Actions

This is a solution of ketamine hydrochloride, an NMDA receptor antagonist, and xylazine hydrochloride, an α₂- adrenergic receptor agonist.

Other Notes

Telephone orders are not accepted for this product.

Kit Components Only

Product No.

Description

Ketamine hydrochloride 80 mg/mL

Xylazine hydrochloride 12 mg/mL

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000308711

0000281028

0000276668

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Myrcene Attenuates Renal Inflammation and Oxidative Stress in the Adrenalectomized Rat Model.

Azim Ullah Shamsul Islam et al.

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Physiological Glucocorticoids are important regulators of the immune system. Pharmacological GCs are in widespread use to treat inflammatory diseases. Adrenalectomy (ADX) has been shown to exacerbate renal injury through inflammation and oxidative stress that results in renal impairment due to

Low- and high-frequency membrane potential oscillations during theta activity in CA1 and CA3 pyramidal neurons of the rat hippocampus under ketamine-xylazine anesthesia.

I Soltesz et al.

Journal of neurophysiology, 70(1), 97-116 (1993-07-01)

1. Intracellularly recorded low- and high-frequency (4-6 and 25-50 Hz, respectively), rhythmic, spontaneous membrane potential oscillations were investigated in pyramidal neurons of the rat hippocampus in vivo, during theta (theta, 4-6 Hz) electroencephalographic (EEG) activity, under ketamine-xylazine anesthesia. 2. The

Exercise and insulin-like growth factor 1 supplementation improve angiogenesis and angiogenic cytokines in a rat model of diabetes-induced neuropathy.

Ehsan Saboory et al.

Experimental physiology, 105(5), 783-792 (2020-02-14)

What is the central question of this study? Do changes in levels of angiogenesis-related mediators [vascular endothelial growth factor-A (VEGF-A), thrombospondin-1 (TSP-1) and nuclear factor-κB (NF-κB)] in the sciatic nerve mediate diabetic neuropathy in the streptozotocin-induced type 1 diabetic male rat?

Different pressor and bronchoconstrictor properties of human big-endothelin-1, 2 (1-38) and 3 in ketamine/xylazine-anaesthetized guinea-pigs.

J P Gratton et al.

British journal of pharmacology, 114(3), 720-726 (1995-02-01)

1. In the present study, the precursors of endothelin-1, endothelin-2 and endothelin-3 were tested for their pressor and bronchoconstrictor properties in the anaesthetized guinea-pig. In addition, the effects of big-endothelin-1 and endothelin-1 were assessed under urethane or ketamine/xylazine anaesthesia. 2.

Restricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway.

Yuanlin He et al.

Cell death & disease, 8(5), e2817-e2817 (2017-05-26)

In mammalian ovaries, primordial follicles remain in a quiescent state until activation by the surrounding microenvironment. Ovarian intervention, for example, ovarian cystectomy, ovarian wedge resection or laser drilling therapies for polycystic ovarian syndrome, has long been reported to change follicular

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Global Trade Item Number

SKU	GTIN
K113-10ML	04061833867907

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