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K1514

Kurtoxin

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About This Item

Empirical Formula (Hill Notation):
C324H478N94O90S8
Molecular Weight:
7386.36
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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form

solid

Quality Segment

shipped in

dry ice

storage temp.

−20°C

General description

Kurtoxin is hydrophobic in nature and shares sequence identity with α-scorpion and has cysteine-stabilized α-helix and β-sheet (CSαβ) motif. It interacts with N-type, and P-type calcium (Ca2+) channels as well.

Application

Kurtoxin has been used as a blocker of T-type and R-Type voltage-gated calcium channels (VGGCs) in hippocampal neurons.

Biochem/physiol Actions

Kurtoxin is isolated from the venom of the South African scorpion Parabuthus transvaalicus. It associates with voltage-gated sodium channels and delays their inactivation.
T-type Ca2+ channel blocker; Scorpion toxin


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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