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K1515

Anti-Kallikrein 11 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Hippostasin, Anti-KLK11

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
3

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~35 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: 1:500-1:1,000

UniProt accession no.

Q9UBX7

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Gene Information

human ... KLK11(11012)
mouse ... Klk11(56538)
rat ... Klk11(292849)

General description

The gene KLK11 (kallikrein 11) encodes a member of the kallikrein gene family. The gene is mapped to human chromosome 19q13.4. It is found to be highly expressed in the prostate. It has been found to be present in biological fluids and in serum of patients with various cancers. KLK11 is also found to be expressed in stomach, trachea, skin, and colon.

Immunogen

synthetic peptide corresponding to residues 68-82 of the human Kallikrein 11. This sequence is 86% identical in mouse and rat.

Biochem/physiol Actions

The gene KLK11 (kallikrein 11) encodes a putative serine protease that is overexpressed in prostate and ovarian cancer. It serves as a biomarker for prognosis of ovarian cancer. It can serve as a marker for distinguishing between prostate cancer and benign prostatic hyperplasia.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
058K1260

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The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Nakamura T
Cancer Research, 63, 6543-6546 (2003)
Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma.
Diamandis EP
Cancer Research, 62, 295-300 (2002)
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Diamandis EP
Clinical Biochemistry, 37, 823-829 (2004)

Related Content

Data Sheet - K1515

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