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Merck
CN

K3628

Kininogen, low molecular weight from human plasma

≥95% (SDS-PAGE), lyophilized powder

Synonym(s):

LMW kininogen

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Technical Service
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biological source

human plasma

Quality Segment

assay

≥95% (SDS-PAGE)

form

lyophilized powder

mol wt

64000 Da

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

Application

Kininogen, low molecular weight from human plasma has been used to study rMASP-1 (recombinant mannose-binding lectin-associated serine protease 1)-mediated cleavage of LK (low molecular weight kininogen). It has been used as a standard for protein identification in milk-proteomics study.

Biochem/physiol Actions

Extracellular cysteine proteinase inhibitor.
LMW kininogen is a major extracellular cysteine proteinase inhibitor. Tissue kallikrein releases bradykinin, a potent bronchoconstrictor and vasoactive agent, from both HMW and LMY kininogen.

Physical form

Lyophilized from a solution in sodium acetate and sodium chloride.


Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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