K4144
KB-R7943
≥98% (HPLC), powder
Synonym(s):
2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester, methanesulfonate (1:1), Carbamimidothioic acid
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About This Item
Empirical Formula (Hill Notation):
C16H17N3O3S·CH3SO3H
CAS Number:
Molecular Weight:
427.50
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
off-white to tan
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1
InChI
1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
InChI key
WGIKEBHIKKWJLG-UHFFFAOYSA-N
Related Categories
Biochem/physiol Actions
KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX.
KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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