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Merck
CN

K4518

PKCγ, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

MGC57564, PKC-gamma, PKCC, PKCG, PRK CG, SCA14

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
Specific activity:
435-589 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
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recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

435-589 nmol/min·mg

mol wt

~105 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PRKCG(5582)

General description

PKCγ (protein kinase C γ) is a s a serine/threonine kinase belonging to the protein kinase C (PKC) family. PKCγ is mainly present in the central nervous system and is strongly expressed in cerebellar Purkinje cells.

Biochem/physiol Actions

PKCγ (protein kinase C γ) is involved in cell proliferation, differentiation as well as migration. Mutations in PKCγ are associated with neurodegenerative disease, spinocerebellar ataxia type 14. Single nucleotide polymorphisms in PKCγ are also linked with high risk of osteosarcoma.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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