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L020000

TCA Deblock

Name: TCA Deblock
Brand: SIGMA

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About This Item

NACRES:

NA.21

UNSPSC Code:

41116105

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type

for DNA synthesis, for DNA synthesis

Quality Level

200

storage condition

dry at room temperature

concentration

28-32 g/L (TCA content, titration)

impurities

≤200 ppm water content (Karl Fischer)

color

clear

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Preparation Note

Trichloroacetic acid / Dichloromethane 3/100 (v/v)

Other Notes

Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

pictograms

GHS08,GHS05,GHS07,GHS09

signalword

Danger

hcodes

H315,H318,H335,H336,H351,H411

pcodes

P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

Regulatory Information

危险化学品

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Global Trade Item Number

SKU	GTIN
L020000-200L	04061837443176
L020000-45L	04061838215390
L020000-4X4L	04061838215413
L020000-4X2.5L	04061838215406
L020000-450ML	04061838215383
L020000-25L	04061837443183

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