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Merck
CN

L023050

DCA Deblock

configured for (ÄKTA® and OligoPilot®)

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About This Item

UNSPSC Code:
41116004
NACRES:
NA.21
Concentration:
42.2-51.6 g/L (DCA content, titration)

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description

with Toluene

Quality Level

200

storage condition

dry at room temperature

concentration

42.2-51.6 g/L (DCA content, titration)

impurities

≤200 ppm water content (Karl Fischer)

color

clear

compatibility

configured for (ÄKTA® and OligoPilot®)

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General description

Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. This solution contains toluene / Dichloroactic Acid (97/3 v/v).

Application

DCA Deblock solution facilitates removal of the DMT that allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

Preparation Note

Toluene / Dichloroacetic acid 97/3 (v/v)

Legal Information

OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Lact. - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system

Storage Class

3 - Flammable liquids

flash_point_f

39.2 °F - closed cup

flash_point_c

4 °C - closed cup

Regulatory Information

易制毒化学品（3类）
危险化学品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
HMBJ9581
HMBK0470
HMBJ7693
HMBK0989
HMBJ8904

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