L0302511
ETT Activator
Synonym(s):
5-(Ethylthio)-1H-tetrazole, 5-(Ethylthio)tetrazole solution
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About This Item
type
for DNA synthesis
Quality Segment
product line
Proligo Reagents
packaging
pkg of 4 × 2.5 L L0302511-04
concentration
39-43 g/L (titration)
impurities
≤30 ppm water content (Karl Fischer)
color
clear
SMILES string
CCSc1nnn[nH]1
InChI
1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)
InChI key
GONFBOIJNUKKST-UHFFFAOYSA-N
General description
ETT activator is an activator solution containing 5-(Ethylthio)-1H-tetrazole – a powerful activator – in acetonitrile. It is mixed with phosphoramidite during the extension step in which it reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
Storage Class
3 - Flammable liquids
flash_point_f
35.6 °F
flash_point_c
2 °C
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