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Merck
CN

L0879

Leu-Leu-Leu

≥90% (elemental analysis), suitable for mass spectrometry (MS)

Synonym(s):

Trileucine

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About This Item

Empirical Formula (Hill Notation):
C18H35N3O4
CAS Number:
Molecular Weight:
357.49
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26
MDL number:
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Product Name

Leu-Leu-Leu, ≥90% (elemental analysis)

Quality Segment

assay

≥90% (elemental analysis)

form

powder

technique(s)

electron microscopy: suitable, mass spectrometry (MS): suitable

color

white

storage temp.

−20°C

SMILES string

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(O)=O

InChI

1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)

InChI key

DNDWZFHLZVYOGF-UHFFFAOYSA-N

Application

Trileucine (Leu-Leu-Leu), an endosome escape moiety, may be used for pH-dependent endosomal membrane disruption to release agents such as antisense oligonucleotides (AONs) inside cells. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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