Skip to Content
Merck
CN

L0881

Lectin from Arachis hypogaea (peanut)

lyophilized powder, Affinity-purified

Synonym(s):

PNA, Peanut agglutinin

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


form

lyophilized powder

Quality Level

potency

<0.1 μg per mL agglutination activity

quality

Affinity-purified

impurities

salt, free

storage temp.

−20°C

General description

Lectin from Arachis hypogaea (peanut) is a homotetrameric protein of 110 kDa.

Application

Lectin from Arachis hypogaea (peanut) has been used:
  • to detect Thomson-Friedenreich antigen
  • as a component in PBS to study its effects on cell viability
  • to study its ability to block the binding site

Biochem/physiol Actions

Lectin from Arachis hypogaea (peanut) possess specificity towards β -D-Gal(1-3)-D-galNAc residue of Thomson − Friedenreich antigen. It is the most widely used diagnostic and prognostic marker for many squamous cell carcinomas.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.

Analysis Note

Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group O erythrocytes after 1 hr incubation at 25 °C.


Still not finding the right product?


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料

This item has



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Related Content

Product Information Sheet


In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell-endothelial cell interaction
Gassmann P
BMC Cancer, 10(1), 177-177 (2010)
Adhesion of plant roots to poly-L-lysine coated polypropylene substrates
Towler MJ and Weathers PJ
Journal of Biotechnology, 101(2), 147-155 (2003)
Alejandro J Cagnoni et al.
Acta crystallographica. Section D, Structural biology, 76(Pt 11), 1080-1091 (2020-11-03)
Carbohydrate-lectin interactions are involved in important cellular recognition processes, including viral and bacterial infections, inflammation and tumor metastasis. Hence, structural studies of lectin-synthetic glycan complexes are essential for understanding lectin-recognition processes and for the further design of promising chemotherapeutics that



Global Trade Item Number

SKUGTIN
L0881-10MG04061833263006
L0881-5MG04061833949061
L0881-25MG04061833949054