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L1290

Lactoferricin B, fragment 4-14 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

bLFC (26-36), bovine lactoferricin

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About This Item

Empirical Formula (Hill Notation):
C70H113N25O13S
Molecular Weight:
1544.87
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD04040902
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Quality Segment

assay

≥95% (HPLC)

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell membrane | interferes

storage temp.

−20°C

General description

Chemical structure: peptide

Application

Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells.

Biochem/physiol Actions

Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens.
Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces.

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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