L1290
Lactoferricin B, fragment 4-14 trifluoroacetate salt
≥95% (HPLC)
Synonym(s):
bLFC (26-36), bovine lactoferricin
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About This Item
Empirical Formula (Hill Notation):
C70H113N25O13S
Molecular Weight:
1544.87
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Quality Segment
assay
≥95% (HPLC)
solubility
H2O: soluble
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell membrane | interferes
storage temp.
−20°C
General description
Chemical structure: peptide
Application
Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells.
Biochem/physiol Actions
Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens.
Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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